What is HCG?
HCG (Human Chorionic Gonadotropin) is a peptide hormone that mimics LH (luteinizing hormone), the signal that tells the testes to produce testosterone. It is used alongside TRT to prevent testicular atrophy, maintain fertility, and preserve natural testosterone production pathways. It is also used for PCT (post-cycle therapy) after SARM or steroid cycles.
Mechanism of Action
HCG binds to LH receptors in Leydig cells of the testes, stimulating testosterone production and maintaining testicular size and function. During TRT, the pituitary stops producing LH (because exogenous testosterone suppresses it), causing testicular atrophy. HCG replaces this LH signal.
HCG Dosing Protocol
TRT adjunct: 500–1,000 IU subcutaneous 2–3 times per week. PCT after SARM/steroid cycle: 500–1,000 IU every other day for 2–4 weeks, then transition to Nolvadex/Clomid. Fertility: 1,500–3,000 IU 3 times per week.
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HCG Benefits
Side Effect Profile
Acne, water retention, potential gynecomastia (HCG stimulates estrogen production in testes), mood changes. Monitor estradiol if using HCG.
HCG Stacking Guide
HCG works synergistically with these compounds. Click any to learn more, or ask PepBot to build you a complete stack.
Research & Citations
Frequently Asked Questions about HCG
Do I need HCG on TRT?
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