What is HGH?
Human Growth Hormone (HGH, Somatropin) is a 191-amino acid peptide hormone produced by the anterior pituitary gland. It is the most powerful anabolic and anti-aging hormone in the body, responsible for growth, body composition, metabolism, and tissue repair. Exogenous HGH is used by athletes, bodybuilders, and anti-aging physicians worldwide.
Mechanism of Action
HGH binds to GH receptors throughout the body, directly stimulating protein synthesis, fat breakdown (lipolysis), and glucose metabolism. It also stimulates the liver to produce IGF-1, which mediates many of HGH's anabolic effects. HGH increases lean mass, reduces fat mass, improves bone density, and has profound anti-aging effects.
HGH Dosing Protocol
Anti-aging/wellness: 1–2 IU/day subcutaneous (low dose, minimal side effects). Body composition: 2–4 IU/day. Performance: 4–6 IU/day (higher side effect risk). Inject subcutaneously, ideally before bed or post-workout on an empty stomach. Cycle: 3–6 months minimum for anti-aging benefits.
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HGH Benefits
Side Effect Profile
Dose-dependent: water retention, carpal tunnel syndrome, joint pain, insulin resistance (glucose intolerance), potential for acromegaly at very high doses. At low doses (1–2 IU/day), generally well-tolerated. Suppresses natural GH production with long-term use.
HGH Stacking Guide
HGH works synergistically with these compounds. Click any to learn more, or ask PepBot to build you a complete stack.
Research & Citations
Frequently Asked Questions about HGH
What is the difference between HGH and GH secretagogues (Ipamorelin, Sermorelin)?
What are optimal IGF-1 levels on HGH?
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